(Source) In causal inference, a counterfactual refers to what would have happened under different conditions or scenarios that did not occur (especially when comparing what actually happened i.e. the observed outcome). It involves considering “what if” scenarios to assess the impact of causal factors.

For a patient who is in the treatment group, what would happen if they had joined the control group? Thinking through counterfactual is a good part of causal inference, because

We would need statistical modeling to fill in predictions for counterfactual, to measure the impact between option A and B (e.g. the difference in outcomes meditation vs fasting), for causal inference later.